Richard Sprague

My personal website

23andme vs. Helix

Created: 2019-01-03 ; Updated: 2020-12-06

Update Jan 2020 Now I have results from Psomagen, added below.

I have genetic test results from 23andme and Helix/Arivale, so I thought it would be interesting to see if they both agree on the SNPs they measure. The answer is yes.

Both of my parents also submitted results and I compared them to mine, finding a few differences here and there, but nothing of serious consequence. Genetic tests have always been disappointing to me because the results rarely seem actionable.


Table 1: Comparing genetic tests
Variant Helix 23andme Psomagen
APOA2 (rs5082) AG AG AG
FTO (rs9939609) AA AA AA
FTO (rs1121980) AA AA AA
SEC16B (rs10913469) CT CT TC
APOA5 (rs662799) AA AA AA
ADRB2 (rs1042714) CC CC CC
ADRB3 (rs4994) AG AG AG
TNF (rs1800629) GG GG GG
TCF7L2 (rs7903146) CC CC CC
PLIN1 (rs894160) CT CT TC
FTO (rs9939609) AA AA AA
TAS2R38 (rs713598) CC CC CC
TAS2R38 (rs1726866) AA AA AA
TAS2R38 (rs10246939) TT TT TT
TAS1R3 (rs35744813) CC No Match TC
SLC2A2 (rs5400) GG GG GG