23andme vs. Helix
Update Jan 2020 Now I have results from Psomagen, added below.
I have genetic test results from 23andme and Helix/Arivale, so I thought it would be interesting to see if they both agree on the SNPs they measure. The answer is yes.
Both of my parents also submitted results and I compared them to mine, finding a few differences here and there, but nothing of serious consequence. Genetic tests have always been disappointing to me because the results rarely seem actionable.
Takeways
I’m more likely to gain weight from saturated fat, though Dad is even more susceptible than I am. We’re equally likely to gain from “healthy” fats.
I’m more likely (than Dad) to gain weight from being sedentary.
Dad is slightly less disposed for a “high waist circumference”, but neither of us is far from the median.
I’m at decreased likelihood to gain weight from carbohydrates. “Eating a diet rich in carbohydrates can actually help prevent weight gain”.
I’m a non-taster (like 28% of the population) for bitter foods (like broccoli). Dad is an intermediate taster and likely to not enjoy them as much.
Like 80% of the population, we are both “typical taste sensitivity to sugar”, meaning we aren’t any more or less susceptible to cravings than most people.
| Variant | Helix | 23andme | Psomagen |
|---|---|---|---|
| APOA2 (rs5082) | AG | AG | AG |
| FTO (rs9939609) | AA | AA | AA |
| FTO (rs1121980) | AA | AA | AA |
| SEC16B (rs10913469) | CT | CT | TC |
| APOA5 (rs662799) | AA | AA | AA |
| ADRB2 (rs1042714) | CC | CC | CC |
| ADRB3 (rs4994) | AG | AG | AG |
| TNF (rs1800629) | GG | GG | GG |
| TCF7L2 (rs7903146) | CC | CC | CC |
| PLIN1 (rs894160) | CT | CT | TC |
| FTO (rs9939609) | AA | AA | AA |
| TAS2R38 (rs713598) | CC | CC | CC |
| TAS2R38 (rs1726866) | AA | AA | AA |
| TAS2R38 (rs10246939) | TT | TT | TT |
| TAS1R3 (rs35744813) | CC | No Match | TC |
| SLC2A2 (rs5400) | GG | GG | GG |